Herb in Thai notifiable formulas
Tinospora Crispa Stem
บอระเพ็ด · Boraphet
Tinospora crispa (L.) Hook.f. & Thomson
- Family
- Menispermaceae
- Part used
- stem (vine)
- Crude drug
- Tinosporae Crispae Caulis
- In the announcement
- Used in 27 notifiable formulas (9 as capsules)
Thai Herbal Pharmacopoeia (THP)
Constituents and quality criteria of Tinospora Crispa Stem
Summarised from the Tinospora Crispa Stem monograph of the Thai Herbal Pharmacopoeia, Department of Medical Sciences, the standard used to test the dried stem.
The pharmacopoeia sets no minimum marker content for this herb. Use the raw material quality criteria below for acceptance testing.
Constituents
Tinospora Crispa Stem contains tinosporine, tinosporidine, picroretin, N-trans -feruloyl tyramine, N-cis -feruloyl tyramine, tinotuberide, borapetoside A, borapetol A, ceryl alcohol, β -sitosterol, stigmasterol, etc.
Raw material quality criteria
| Foreign matter | Not more than 2.0% w/w |
| Loss on drying | Not more than 11.0% w/w |
| Total ash | Not more than 7.0% w/w |
| Acid-insoluble ash | Not more than 0.5% w/w |
| Water-soluble extractive | Not less than 10.0% w/w |
| Determination of bitterness | Not less than 210 units per g |
| Ethanol-soluble extractive | Not less than 5.0% w/w |
Storage: Tinospora Crispa Stem shall be kept in well-closed containers, protected from light, and stored in a dry place.
Source: Thai Herbal Pharmacopoeia, Department of Medical Sciences (online edition, accessed 21 October 2026)Read the full THP monograph
Formulas using Tinospora Crispa Stem
27 formulas containing Tinospora Crispa Stem
Select a formula to see its ingredients and indications. Formula names and indications are a reference translation; the Thai announcement is the legal text.
- Ya Chanthalila Traditional formula for feverRelieves fever (khai tua ron) and fever with the change of seasons (khai plian rudu)
- Ya Wisamphaya Yai Traditional formula for bloating and colicRelieves abdominal bloating, flatulence and abdominal colic/flatulent discomfort
- Ya Prasa Chettaphangkhi Chettaphangkhi (Cladogynos) formula for colic and windRelieves kasai (a chronic wasting condition in Thai traditional medicine) with abdominal colic/flatulent discomfort, expels flatus
- Ya Bamrung That Lang Fuen Khai Element tonic after recovering from feverElement tonic (bamrung that) after recovery from fever, fire-element tonic (bamrung fai that), promotes appetite
- Ya Bencha That Five-element formula for wind and appetiteCarminative (relieves flatulence), element tonic (bamrung that), promotes appetite
- Ya Kae Khai Phuea Samha Formula for phlegm-type feverRelieves fever due to phlegm (khai phuea samha) (fever with alternating hot flushes and chills, having a cold)
- Ya Patolathikhun Traditional formula for fever with phlegmRelieves fever due to heat and phlegm (khai phuea kamdao lae samha); relieves fever recurring every other day (khai chap wan wen wan)
- Tamrap Samunphrai Bamrung Rang Kai Formula 5 Herbal body tonic, Formula 5Helps increase appetite
- Tamrap Samunphrai Chuai Nai Kan Khap Thai Herbal formula for bowel movementHelps with bowel movements
- Ya Chanthalila Traditional formula for feverRelieves fever (khai tua ron) and fever with the change of seasons (khai plian rudu)
- Ya Chanthalila Traditional formula for feverRelieves fever (khai tua ron) and fever with the change of seasons (khai plian rudu)
- Ya Hom Inthachak Fragrant formula for faintness and nauseaRelieves lom bat tha chit (a wind (lom) disorder affecting the mind), relieves nausea and vomiting, relieves wind (lom) causing abdominal colic/flatulent discomfort
- Ya Hom Inthachak Fragrant formula for faintness and nauseaRelieves lom bat tha chit (a wind (lom) disorder affecting the mind), relieves nausea and vomiting, relieves wind (lom) causing abdominal colic/flatulent discomfort
- Ya Hom Nawakot Fragrant nine-kot formula for dizziness and nauseaRelieves dizziness due to wind (lom wing wian), nausea and vomiting (wind causing tightness in the chest, lom chuk naen nai ok) in the elderly; relieves post-fever wind (lom plai khai) (after recovering from fever, symptoms remain such as nausea, dizziness, loss of appetite, abdominal bloating and fatigue)
- Ya Wisamphaya Yai Traditional formula for bloating and colicRelieves abdominal bloating, flatulence and abdominal colic/flatulent discomfort
- Ya Prasa Chettaphangkhi Chettaphangkhi (Cladogynos) formula for colic and windRelieves kasai (a chronic wasting condition in Thai traditional medicine) with abdominal colic/flatulent discomfort, expels flatus
- Ya Bamrung That Lang Fuen Khai Element tonic after recovering from feverElement tonic (bamrung that) after recovery from fever, fire-element tonic (bamrung fai that), promotes appetite
- Ya Bamrung That Lang Fuen Khai Element tonic after recovering from feverElement tonic (bamrung that) after recovery from fever, fire-element tonic (bamrung fai that), promotes appetite
- Ya Bencha That Five-element formula for wind and appetiteCarminative (relieves flatulence), element tonic (bamrung that), promotes appetite
- Ya Kae Ai Mai Mi Samha Formula 3 Formula for dry cough, Formula 3Relieves cough without phlegm
- Ya Kae Khai Phuea Samha Formula for phlegm-type feverRelieves fever due to phlegm (khai phuea samha) (fever with alternating hot flushes and chills, having a cold)
- Ya Kae Khai Phuea Samha Formula for phlegm-type feverRelieves fever due to phlegm (khai phuea samha) (fever with alternating hot flushes and chills, having a cold)
- Ya Patolathikhun Traditional formula for fever with phlegmRelieves fever due to heat and phlegm (khai phuea kamdao lae samha); relieves fever recurring every other day (khai chap wan wen wan)
- Ya Patolathikhun Traditional formula for fever with phlegmRelieves fever due to heat and phlegm (khai phuea kamdao lae samha); relieves fever recurring every other day (khai chap wan wen wan)
- Tamrap Samunphrai Bamrung Rang Kai Formula 1 Herbal body tonic, Formula 1Helps nourish the body (body tonic)
- Tamrap Samunphrai Bamrung Rang Kai Formula 5 Herbal body tonic, Formula 5Helps increase appetite
- Tamrap Samunphrai Chuai Nai Kan Khap Thai Herbal formula for bowel movementHelps with bowel movements
Development potential
Develop Tinospora Crispa Stem into a product with the TIBD group
In notifiable formulas27 formulasused in multi-herb formulas
THP raw-material criteria7 testsfor acceptance testing before production
Marker with a minimum contentNot setquality is checked with the raw-material criteria
Three ways forward 1Notify a listed formula2Adapt it through detailed notification3Develop a Category B herbal medicine or Category C health productSee the development pathway
K-API · manufacturing in the group
Extract and manufacture at K-API
The TIBD group plant licensed by the Thai FDA to manufacture herbal products, so extraction and production stay within the group.
See the K-API plantTIBD · consultationPlan a product with Tinospora Crispa Stem
We check whether your formula qualifies for notification, detailed notification or registration with the Thai FDA, then prepare the filing documents.
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