Herb in Thai notifiable formulas

Kaffir Lime

มะกรูด · Makrut

Citrus hystrix DC.

Family
Rutaceae
Part used
peel
Crude drug
Citri Hystricis Folium
Other names
Kaffir Lime Leaf, Leech Lime Leaf, Mauritius Papeda Leaf, Porcupine Orange Leaf
In the announcement
Used in 22 notifiable formulas (6 as capsules)
Kaffir Lime, dried leaf
Photo: Jiafei Slay Queen · Wikimedia Commons · CC0 · resized
Thai Herbal Pharmacopoeia (THP)

Constituents and quality criteria of Kaffir Lime

Summarised from the Citrus Hystrix Leaf monograph of the Thai Herbal Pharmacopoeia, Department of Medical Sciences, the standard used to test the dried leaf.

The pharmacopoeia sets no minimum marker content for this herb. Use the raw material quality criteria below for acceptance testing.

Constituents

Citrus Hystrix Leaf contains volatile oil, of which citronellal, citronellol and citronellol acetate are its major components; sabinene, α - and β -pinene, α -phellandrene, limonene, α - and γ -terpinene, cymene, linalool, indole alkaloids are also found. It also contains rutin, hesperidin and diosmin.

The THP monograph covers the leaf, while the formulas mainly use the fruit peel, so the quality criteria on this page apply to the leaf only.

Raw material quality criteria

Foreign matterNot more than 2.0% w/w
Total ashNot more than 17.0% w/w
Acid-insoluble ashNot more than 3.0% w/w
Water-soluble extractiveNot less than 18.0% w/w
Ethanol-soluble extractiveNot less than 6.0% w/w
Volatile oilNot less than 0.6% v/w

Storage: Citrus Hystrix Leaf shall be kept in well-closed containers, preferably of metal or glass, protected from light and stored in a cool and dry place. It should be used within 1 year and air-dried every 2 to 3 months.

Source: Thai Herbal Pharmacopoeia, Department of Medical Sciences (online edition, accessed 21 October 2026)Read the full THP monograph
Formulas using Kaffir Lime

22 formulas containing Kaffir Lime

Select a formula to see its ingredients and indications. Formula names and indications are a reference translation; the Thai announcement is the legal text.

Development potential

Develop Kaffir Lime into a product with the TIBD group

In notifiable formulas22 formulasused in multi-herb formulas
THP raw-material criteria6 testsfor acceptance testing before production
Marker with a minimum contentNot setquality is checked with the raw-material criteria
Testing in the groupVISBIOVolatile compound analysis by GC-MS

Three ways forward 1Notify a listed formula2Adapt it through detailed notification3Develop a Category B herbal medicine or Category C health productSee the development pathway