Herb in Thai notifiable formulas
Bridelia Ovata Leaf
มะกา · Maka
Bridelia ovata Decne.
- Family
- Phyllanthaceae
- Part used
- leaf
- Crude drug
- Brideliae Ovatae Folium
- In the announcement
- Used in 5 notifiable formulas (2 as capsules)
Thai Herbal Pharmacopoeia (THP)
Constituents and quality criteria of Bridelia Ovata Leaf
Summarised from the Bridelia Ovata Leaf monograph of the Thai Herbal Pharmacopoeia, Department of Medical Sciences, the standard used to test the dried leaf.
The pharmacopoeia sets no minimum marker content for this herb. Use the raw material quality criteria below for acceptance testing.
Constituents
Bridelia Ovata Leaf contains triterpenoids such as friedelin. It also contains sterols, etc.
Raw material quality criteria
| Foreign matter | Not more than 2.0% w/w |
| Loss on drying | Not more than 7.0% w/w |
| Total ash | Not more than 12.0% w/w |
| Acid-insoluble ash | Not more than 1.0% w/w |
| Water-soluble extractive | Not less than 13.0% w/w |
| Ethanol-soluble extractive | Not less than 5.0% w/w |
Storage: Bridelia Ovata Leaf shall be kept in well-closed containers, protected from light, and stored in a dry place. Identication A. To 500 mg of the sample, in powder, add 10 mL of methanol, shake, allow to stand for 20 minutes, and filter. Evaporate 2 mL of the filtrate to dry and dissolve the residue i.
Source: Thai Herbal Pharmacopoeia, Department of Medical Sciences (online edition, accessed 21 October 2026)Read the full THP monograph
Formulas using Bridelia Ovata Leaf
5 formulas containing Bridelia Ovata Leaf
Select a formula to see its ingredients and indications. Formula names and indications are a reference translation; the Thai announcement is the legal text.
- Ya Thai Di Kluea Farang Epsom salt laxative formula for constipationRelieves constipation
- Tamrap Samunphrai Chuai Rabai Herbal laxative formulaHelps with bowel movements
- Ya Phai Lohit Formula for scanty menstruation with clotsRelieves menstruation that is lighter than normal, with clots or lumps (sold only at licensed premises)
- Ya Thai Khai Phit Khai Kan Purgative formula for toxic fever (khai phit, khai kan)Purges toxic fever (khai phit) and kan fever (khai kan)
- Tamrap Samunphrai Chuai Rabai Herbal laxative formulaHelps with bowel movements
Development potential
Develop Bridelia Ovata Leaf into a product with the TIBD group
In notifiable formulas5 formulasused in multi-herb formulas
THP raw-material criteria6 testsfor acceptance testing before production
Marker with a minimum contentNot setquality is checked with the raw-material criteria
Three ways forward 1Notify a listed formula2Adapt it through detailed notification3Develop a Category B herbal medicine or Category C health productSee the development pathway
K-API · manufacturing in the group
Extract and manufacture at K-API
The TIBD group plant licensed by the Thai FDA to manufacture herbal products, so extraction and production stay within the group.
See the K-API plantTIBD · consultationPlan a product with Bridelia Ovata Leaf
We check whether your formula qualifies for notification, detailed notification or registration with the Thai FDA, then prepare the filing documents.
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