Herb in Thai notifiable formulas
Andrographis
ฟ้าทะลายโจร · Fa Thalai Chon
Andrographis paniculata (Burm. f.) Nees
- Family
- Acanthaceae
- Part used
- aerial part
- Crude drug
- Andrographitis Herba
- In the announcement
- Used in 2 notifiable formulas (2 as capsules)
Thai Herbal Pharmacopoeia (THP)
Constituents and quality criteria of Andrographis
Summarised from the Andrographis Herb monograph of the Thai Herbal Pharmacopoeia, Department of Medical Sciences, the standard used to test the dried aerial part.
Marker with a minimum content set by the pharmacopoeiaTotal lactones, calculated as andrographolide
CriterionNot less than 6.0% w/w
Constituents
Andrographis Herb contains a large quantity of bitter diterpenoid lactones which mainly are andrographolide, neoandrographolide, 14-deoxy-11,12-didehydroandrographolide (dehydroandrographolide), dideoxyandrographolide (andrograpanin), etc. and their glycosides. It also contains β-sitosterol-D-glucoside, flavonoids, etc.
Raw material quality criteria
| Foreign matter | Not more than 2.0% w/w |
| Loss on drying | Not more than 11.0% w/w |
| Acid-insoluble ash | Not more than 2.0% w/w |
| Ethanol (85 per cent)-soluble extractive | Not less than 13.0% w/w |
| Water-soluble extractive | Not less than 18.0% w/w |
Storage: Andrographis Herb shall be kept in well-closed containers, protected from light, and stored in a dry place. It should be used within 1 year and air-dried every 2 to 3 months.
Source: Thai Herbal Pharmacopoeia, Department of Medical Sciences (online edition, accessed 21 October 2026)Read the full THP monograph
Formulas using Andrographis
2 formulas containing Andrographis
Select a formula to see its ingredients and indications. Formula names and indications are a reference translation; the Thai announcement is the legal text.
Development potential
Develop Andrographis into a product with the TIBD group
In notifiable formulas2 formulas2 as a single-herb formula
THP raw-material criteria5 testsfor acceptance testing before production
Marker with a minimum contentNot less than 6.0% w/wTotal lactones, calculated as andrographolide
Testing in the groupVISBIOAndrographolide content testing
Three ways forward 1Notify a listed formula2Adapt it through detailed notification3Develop a Category B herbal medicine or Category C health productSee the development pathway
VISBIO · laboratory in the TIBD group
Andrographolide content testing
Analytical testing of Andrographis raw materials and products by VISBIO, the laboratory in our group.
See the VISBIO serviceK-API · manufacturing in the groupExtract and manufacture at K-API
The TIBD group plant licensed by the Thai FDA to manufacture herbal products, so extraction and production stay within the group.
See the K-API plantTIBD · consultationPlan a product with Andrographis
We check whether your formula qualifies for notification, detailed notification or registration with the Thai FDA, then prepare the filing documents.
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