Herb in Thai notifiable formulas

Harrisonia Perforata Root

คนทา · Khon Tha

Harrisonia perforata (Blanco) Merr.

Family: Rutaceae
Part used: root
Crude drug: Harrisoniae Perforatae Radix Harrisonia Perorata Root
In the announcement: Used in 2 notifiable formulas (1 as capsules)

Harrisonia Perforata Root, dried root — AI-generated illustration based on the crude drug description in the Thai Herbal Pharmacopoeia; not a photograph of an actual sample.

Thai Herbal Pharmacopoeia (THP)

Constituents and quality criteria of Harrisonia Perforata Root

Summarised from the Harrisonia Perforata Root monograph of the Thai Herbal Pharmacopoeia, Department of Medical Sciences, the standard used to test the dried root.

The pharmacopoeia sets no minimum marker content for this herb. Use the raw material quality criteria below for acceptance testing.

Constituents

Harrisonia Perforata Root contains limonoids (e.g., harperfolide, harrisonin, obacunone) and chromones (e.g., harperamone). It also contains coumarins, sterols, etc.

Raw material quality criteria

Foreign matter	Not more than 2.0% w/w
Loss on drying	Not more than 9.0% w/w
Total ash	Not more than 4.0% w/w
Water-soluble extractive	Not less than 3.0% w/w
Ethanol-soluble extractive	Not less than 2.0% w/w

Storage: Harrisonia Perforata Root shall be kept in well-closed containers, protected from light, and stored in a dry place.

Source: Thai Herbal Pharmacopoeia, Department of Medical Sciences (online edition, accessed 21 October 2026)Read the full THP monograph

Formulas using Harrisonia Perforata Root

2 formulas containing Harrisonia Perforata Root

Select a formula to see its ingredients and indications. Formula names and indications are a reference translation; the Thai announcement is the legal text.

Development potential

Develop Harrisonia Perforata Root into a product with the TIBD group

In notifiable formulas2 formulasused in multi-herb formulas

THP raw-material criteria5 testsfor acceptance testing before production

Marker with a minimum contentNot setquality is checked with the raw-material criteria

Three ways forward 1Notify a listed formula2Adapt it through detailed notification3Develop a Category B herbal medicine or Category C health productSee the development pathway

K-API · manufacturing in the group

Extract and manufacture at K-API

The TIBD group plant licensed by the Thai FDA to manufacture herbal products, so extraction and production stay within the group.

See the K-API plant TIBD · consultation

Plan a product with Harrisonia Perforata Root

We check whether your formula qualifies for notification, detailed notification or registration with the Thai FDA, then prepare the filing documents.

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